Developmental score of the infant brain: characterizing diffusion MRI in term- and preterm-born infants

Large-scale longitudinal neuroimaging studies of the infant brain allow us to map the spatiotemporal development of the brain in its early phase. While the postmenstrual age (PMA) is commonly used as a time index to analyze longitudinal MRI data, the nonlinear relationship between PMA and MRI data imposes challenges for downstream analyses. We propose a mathematical model that provides a Developmental Score (DevS) as a data-driven time index to...