Kupffer cell inactivation ameliorates immune liver injury via TNF-α/TNFR1 signal pathway in trichloroethylene sensitized mice
Volume: 42, Issue: 6, Pages: 545 - 555
Published: Sep 13, 2020
Abstract
Aim: The present study aims to explore the important role of Kupffer cell and its related cytokine TNF-α in immune liver injury induced by trichloroethylene (TCE).Methods 36 female BALB/c mice were selected and randomly divided the mice into four groups. We established a BALB/c mouse model of TCE sensitization and pretreatment with GdCl3 (40 mg/kg) by intraperitoneal injection during the during the 17th and 19th days.Results We found F4/80, the...
Paper Details
Title
Kupffer cell inactivation ameliorates immune liver injury via TNF-α/TNFR1 signal pathway in trichloroethylene sensitized mice
Published Date
Sep 13, 2020
Volume
42
Issue
6
Pages
545 - 555
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