Give Gluten a Chance! Time to Schedule Gluten Re-introduction in Celiac Patients on a Long-term Gluten-free Diet?

To the Editor: A strict life-long gluten-free Diet (GFD) is the only therapy for celiac disease (CeD) (1). GFD is considered an untouchable dogma but some concerns about its use (strictness and chronicity) and the possible development of gluten tolerance, are objectively real (2). Several studies investigated this issue. A first attempt evaluated the re-introduction of gluten and demonstrated that 11% of patients tolerated it (3), similarly to 3...