Rapid Determination of Antimicrobial Susceptibility by Stimulated Raman Scattering Imaging of D 2 O Metabolic Incorporation in a Single Bacterium

Volume: 7, Issue: 19, Pages: 2001452 - 2001452
Published: Aug 16, 2020
Abstract
Rapid antimicrobial susceptibility testing (AST) is urgently needed for treating infections with appropriate antibiotics and slowing down the emergence of antibiotic-resistant bacteria. Here, a phenotypic platform that rapidly produces AST results by femtosecond stimulated Raman scattering imaging of deuterium oxide (D2 O) metabolism is reported. Metabolic incorporation of D2 O into biomass in a single bacterium and the metabolic response to...
Paper Details
Title
Rapid Determination of Antimicrobial Susceptibility by Stimulated Raman Scattering Imaging of D 2 O Metabolic Incorporation in a Single Bacterium
Published Date
Aug 16, 2020
Volume
7
Issue
19
Pages
2001452 - 2001452
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