Advances in oligonucleotide drug delivery
Abstract
Oligonucleotides can be used to modulate gene expression via a range of processes including RNAi, target degradation by RNase H-mediated cleavage, splicing modulation, non-coding RNA inhibition, gene activation and programmed gene editing. As such, these molecules have potential therapeutic applications for myriad indications, with several oligonucleotide drugs recently gaining approval. However, despite recent technological advances, achieving...
Paper Details
Title
Advances in oligonucleotide drug delivery
Published Date
Aug 11, 2020
Volume
19
Issue
10
Pages
673 - 694
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