Editors' note: Intrathecal IgM production is a strong risk factor for early conversion to multiple sclerosis

Volume: 95, Issue: 6, Pages: 276.2 - 276
Published: Aug 10, 2020
Abstract
In their prospective, observational cohort of 150 patients with clinically isolated syndrome (CIS) or early relapsing-remitting multiple sclerosis (RRMS), Drs. Pfuhl et al. found that intrathecal IgM levels were significantly and independently predictive of conversion from CIS to RRMS. In a multivariable Cox regression, the presence of intrathecal IgM antibodies even outperformed oligoclonal bands and intrathecal IgG antibodies as a predictor...
Paper Details
Title
Editors' note: Intrathecal IgM production is a strong risk factor for early conversion to multiple sclerosis
Published Date
Aug 10, 2020
Journal
Volume
95
Issue
6
Pages
276.2 - 276
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