Elucidating the fundamental fibrotic processes driving abdominal adhesion formation

Volume: 11, Issue: 1
Published: Aug 13, 2020
Abstract
Adhesions are fibrotic scars that form between abdominal organs following surgery or infection, and may cause bowel obstruction, chronic pain, or infertility. Our understanding of adhesion biology is limited, which explains the paucity of anti-adhesion treatments. Here we present a systematic analysis of mouse and human adhesion tissues. First, we show that adhesions derive primarily from the visceral peritoneum, consistent with our clinical...
Paper Details
Title
Elucidating the fundamental fibrotic processes driving abdominal adhesion formation
Published Date
Aug 13, 2020
Volume
11
Issue
1
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