In vitro augmentation of chondrogenesis by Epigallocatechin gallate in primary Human chondrocytes - Sustained release model for cartilage regeneration

Epigallocatechin-3-gallate (EGCG), a plant polyphenol catechin is potent chondrogenic drug which enhances cartilage regeneration. Hence, sustained release of EGCG from interlinked porous polycaprolactone (PCL) scaffolds can be beneficial in engineering a cartilage construct. In this study, 10% (w/v) and 12% (w/v) PCL scaffold were fabricated by incorporation of 2 different concentrations (1 mg/ml & 2 mg/ml) of EGCG loaded albumin nanoparticles...