Molecular analysis of streptomycin-resistance associating genes in Mycobacterium tuberculosis isolates from Nepal
Abstract
Mutation in rpsL (encoding ribosomal protein S12), rrs (encoding 16S ribosomal RNA) and gidB (encoding 7-methylguanosine methyltransferase) are associated with resistance to streptomycin (STR), which is used for the treatment of multi-drug resistant tuberculosis (MDR-TB) in Nepal. The aim of our study is to analyze the correlation between mutations in the target genes and STR-resistance in 197 Mycobacterium tuberculosis (MTB) isolates from...
Paper Details
Title
Molecular analysis of streptomycin-resistance associating genes in Mycobacterium tuberculosis isolates from Nepal
Published Date
Dec 1, 2020
Journal
Volume
125
Pages
101985 - 101985
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