Laminins Regulate Placentation and Pre-eclampsia: Focus on Trophoblasts and Endothelial Cells

Volume: 8
Published: Aug 7, 2020
Abstract
Pre-eclampsia is a systemic vascular disease characterized by new-onset hypertension and/or proteinuria at ≥20 weeks of gestation and leads to high rates of maternal and perinatal morbidity and mortality. Despite the incomplete understanding of pre-eclampsia pathophysiology, it is accepted that insufficient spiral artery remodeling and endothelial dysfunction are major contributors. Laminins (LNs) are a vital family of extracellular matrix...
Paper Details
Title
Laminins Regulate Placentation and Pre-eclampsia: Focus on Trophoblasts and Endothelial Cells
Published Date
Aug 7, 2020
Volume
8
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