Targeting Dysregulation of Metalloproteinase Activity in Osteoarthritis

Volume: 109, Issue: 3, Pages: 277 - 290
Published: Aug 9, 2020
Abstract
Metalloproteinases were first identified as collagen cleaving enzymes and are now appreciated to play important roles in a wide variety of biological processes. The aberrant activity and dysregulation of the metalloproteinase family are linked to numerous diseases including cardiovascular and pulmonary diseases, chronic wounds, cancer, fibrosis and arthritis. Osteoarthritis (OA) is the most prevalent age-related joint disorder that causes pain...
Paper Details
Title
Targeting Dysregulation of Metalloproteinase Activity in Osteoarthritis
Published Date
Aug 9, 2020
Volume
109
Issue
3
Pages
277 - 290
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