Directly Acting Antivirals for COVID-19: Where Do We Stand?

Siew Li Teoh; Yi H. Lim; Nai Ming Lai; Shaun Wen Huey Lee

doi:https://doi.org/10.3389/fmicb.2020.01857

doi.org/10.3389/fmicb.2020.01857

Directly Acting Antivirals for COVID-19: Where Do We Stand?

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..., Shaun Wen Huey Lee

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Frontiers in Microbiology5.20

Volume: 11

Published: Aug 5, 2020

Abstract

The outbreak of a novel coronavirus (SARS-CoV-2) in Wuhan, China in December 2019 has now become a pandemic with no approved therapeutic agent. At the moment, the genomic structure, characteristics and pathogenic mechanisms of SARS-CoV-2 have been reported. Based upon this information, several drugs including the directly acting antivirals have been proposed to treat people with coronavirus disease 2019 (COVID-19). This rapid review aims to...