Characteristics of Hemichannel-Mediated Substrate Transport in Human Retinal Pigment Epithelial Cells under Deprivation of Extracellular Ca<sup>2+</sup>
Volume: 43, Issue: 8, Pages: 1241 - 1247
Published: Aug 1, 2020
Abstract
Retinal pigment epithelial (RPE) cells form the outer blood–retinal barrier (BRB) and regulate drug/compound exchange between the neural retina and blood in the fenestrated blood vessels of retinal choroid via membrane transporters. Recent studies have elucidated that RPE cells express hemichannels, which are opened by extracellular Ca2+ depletion and accept several drugs/compounds as a transporting substrate. The objective of this study was to...
Paper Details
Title
Characteristics of Hemichannel-Mediated Substrate Transport in Human Retinal Pigment Epithelial Cells under Deprivation of Extracellular Ca<sup>2+</sup>
Published Date
Aug 1, 2020
Volume
43
Issue
8
Pages
1241 - 1247
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