Collagen, stiffness, and adhesion: the evolutionary basis of vertebrate mechanobiology
Abstract
The emergence of collagen I in vertebrates resulted in a dramatic increase in the stiffness of the extracellular environment, supporting long-range force propagation and the development of low-compliant tissues necessary for the development of vertebrate traits including pressurized circulation and renal filtration. Vertebrates have also evolved integrins that can bind to collagens, resulting in the generation of higher tension and more...
Paper Details
Title
Collagen, stiffness, and adhesion: the evolutionary basis of vertebrate mechanobiology
Published Date
Aug 1, 2020
Volume
31
Issue
17
Pages
1823 - 1834
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