Combination of matrix solid phase dispersion and response surface evaluation for simultaneous detections of multiple bioactive constituents of traditional Chinese medicine formula: Using Baoyuan Capsule as an example

Traditional Chinese Medicine (TCM) formulae contain abundant chemical ingredients, leading to the development of high quality TCM productions be difficult. With different pharmacokinetic and pharmacodynamic parameters of the chemical ingredients in a TCM formula, it is desirable to simultaneously identify multiple ingredients for accurate quality control. In the present study, we introduce a novel strategy for TCM formula quality assessment by...