Co-Amorphization of Kanamycin with Amino Acids Improves Aerosolization
Abstract
Different formulation techniques have been investigated to prepare highly aerosolizable dry powders to deliver a high dose of antibiotics to the lung for treating local infections. In this study, we investigated the influence of the co-amorphization of a model drug, kanamycin, with selected amino acids (valine, methionine, phenylalanine, and tryptophan) by co-spray drying on its aerosolization. The co-amorphicity was confirmed by thermal...
Paper Details
Title
Co-Amorphization of Kanamycin with Amino Acids Improves Aerosolization
Published Date
Jul 30, 2020
Journal
Volume
12
Issue
8
Pages
715 - 715
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