Specific macrophage subsets accumulate in human subcutaneous and omental fat depots during obesity

Obesity is a chronic inflammatory disease associated with adipose tissue macrophage (ATM) activation. ATMs from lean mice contribute to tissue homeostasis by their M2‐oriented polarization, whereas obesity leads to an increase of M1 inflammatory ATMs that underlies obesity‐related metabolic disorders. In humans, studies characterizing ATMs and their functional status are limited. Here we investigated ATM phenotype in visceral (VAT) and...