Adaptive T cell immunotherapy in cancer
Abstract
Impaired tumor-specific effector T cells contribute to tumor progression and unfavorable clinical outcomes. As a compensatory T cell-dependent cancer immunoediting strategy, adoptive T cell therapy (ACT) has achieved encouraging therapeutic results, and this strategy is now on the center stage of cancer treatment and research. ACT involves the ex vivo stimulation and expansion of tumor-infiltrating lymphocytes (TILs) with inherent tumor...
Paper Details
Title
Adaptive T cell immunotherapy in cancer
Published Date
Jul 23, 2020
Journal
Volume
64
Issue
3
Pages
363 - 371
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