Effects of polygenic risk for Alzheimer’s disease on rate of cognitive decline in normal aging
Abstract
Most people’s cognitive abilities decline with age, with significant and partly genetically driven, individual differences in rate of change. Although APOE ɛ4 and genetic scores for late-onset Alzheimer’s disease (LOAD) have been related to cognitive decline during preclinical stages of dementia, there is limited knowledge concerning genetic factors implied in normal cognitive aging. In the present study, we examined three potential genetic...
Paper Details
Title
Effects of polygenic risk for Alzheimer’s disease on rate of cognitive decline in normal aging
Published Date
Jul 24, 2020
Journal
Volume
10
Issue
1
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