Single-cell RNA sequencing reveals the cellular heterogeneity of aneurysmal infrarenal abdominal aorta
Abstract
The artery contains numerous cell types which contribute to multiple vascular diseases. However, the heterogeneity and cellular responses of these vascular cells during abdominal aortic aneurysm (AAA) progression have not been well characterized.Single-cell RNA sequencing was performed on the infrarenal abdominal aortas (IAAs) from C57BL/6J mice at Days 7 and 14 post-sham or peri-adventitial elastase-induced AAA. Unbiased clustering analysis of...
Paper Details
Title
Single-cell RNA sequencing reveals the cellular heterogeneity of aneurysmal infrarenal abdominal aorta
Published Date
Jul 17, 2020
Journal
Volume
117
Issue
5
Pages
1402 - 1416
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