8-prenylgenistein exerts osteogenic effects via ER α and Wnt-dependent signaling pathway
Abstract
8-prenylgenistein (8PG) was previously reported to exert stronger osteogenic activity than genistein, a well-known soy phytoestrogen. However, the molecular mechanism underlying the actions of 8PG on osteoblasts was far from clear. In the present study, the osteogenic effects and mechanisms of 8PG and genistein were studied using human BMSC and murine pre-osteoblast MC3T3-E1 cells. Our results indicated that the stimulatory effects of 8PG and...
Paper Details
Title
8-prenylgenistein exerts osteogenic effects via ER α and Wnt-dependent signaling pathway
Published Date
Oct 1, 2020
Journal
Volume
395
Issue
1
Pages
112186 - 112186
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