Transition metal

Conjugated system

Physical chemistry

Catalysis

Electrode

Natural rubber

Organic chemistry

Chemistry

Electrosynthesis

Combinatorial chemistry

Carboxylation

Alkene

Diene

Carboxylic acid

Polymer

Electrochemistry

Osmium

Ruthenium

Chemical Science

To date the majority of diene carboxylation processes afford the α,δ-dicarboxylated product, the selective mono-carboxylation of dienes is a significant challenge and the major product reported under transition metal catalysis arises from carboxylation at the α-carbon. Herein we report a new electrosynthetic approach, that does not rely on a sacrificial electrode, the reported method allows unprecedented direct access to carboxylic acids derived from dienes at the δ-position. In addition, the α,δ-dicarboxylic acid or the α,δ-reduced alkene can be easily accessed by simple modification of the reaction conditions.

Selective α,δ-hydrocarboxylation of conjugated dienes utilizing CO<sub>2</sub> and electrosynthesis

Selective α,δ-hydrocarboxylation of conjugated dienes utilizing CO2 and electrosynthesis

Selective α,δ-hydrocarboxylation of conjugated dienes utilizing CO₂ and electrosynthesis