Adventitial matrix metalloproteinase production and distribution of immunoglobulin G4-related abdominal aortic aneurysms
Abstract
IgG4-related diseases are systemic inflammatory fibrous lesions characterized by elevated serum IgG4 and infiltration of IgG4-positive plasmacytes. They can manifest in vascular lesions as frequently formed aneurysms with prominent thickening of the adventitia (IgG4-related abdominal aortic aneurysm; IgG4-AAA). Matrix metalloproteinases (MMPs) degrade the extracellular matrix, mainly in the tunica media, resulting in destruction of aortic...
Paper Details
Title
Adventitial matrix metalloproteinase production and distribution of immunoglobulin G4-related abdominal aortic aneurysms
Published Date
Jan 1, 2020
Journal
Volume
1
Pages
151 - 165
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