Tryophagus putrescentiae induces inflammatory cytokine secretions from the human cell lines THP‐1 and EoL‐1 cells

The present study aimed to identify the roles of the storage mite Tyrophagus putrescentiae (Tp) in relation to human skin diseases, such as atopic dermatitis. We examined the effects of T. putrescentiae extracts (TpE) on the secretion of inflammatory cytokines and their mRNA expression in human immune cells. Human monocytic THP‐1 and eosinophilic EoL‐1 cells were challenged with TpE and the inflammatory cytokines, interleukin‐6 (IL‐6),...