Plasma proteomics and lung function in four community-based cohorts

Underlying mechanism leading to impaired lung function are incompletely understood.To investigate whether protein profiling can provide novel insights into mechanisms leading to impaired lung function.We used four community-based studies (n = 2552) to investigate associations between 79 cardiovascular/inflammatory proteins and forced expiratory volume in 1 s percent predicted (FEV1%) assessed by spirometry. We divided the cohorts into discovery...