Assessing anti-estrogenic effects of AHR ligands in primary human and rat endometrial epithelial cells

Volume: 96, Pages: 202 - 208
Published: Sep 1, 2020
Abstract
Unopposed estrogenic action in the uterus can lead to the development of endometrial cancer in both humans and rats. Aryl hydrocarbon receptor (AHR) activation gives rise to anti-estrogenic actions and may consequently reduce the development of endometrial cancer. In this study, the anti-estrogenic potential of the AHR ligands 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and DELAQ, a metabolite of the pharmaceutical laquinimod, was assessed in in...
Paper Details
Title
Assessing anti-estrogenic effects of AHR ligands in primary human and rat endometrial epithelial cells
Published Date
Sep 1, 2020
Volume
96
Pages
202 - 208
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