Ten new glycosides, carissaedulosides A–J from the root barks of Carissa edulis and their cytotoxicities

Ten previously undescribed glycosides, carissaedulosides A–J (1–10) referring to six apiosylated phenylpropanoids (1–6), one coumarin-secoiridoid hybrid (7), and three furofuran lignans (8–10) were isolated from the root barks of Carissa edulis, together with 13 known analogues (11–23). Their structures were elucidated by spectroscopic analysis, ECD computational methods, and chemical derivations for configurations of sugar moieties. The new...