Progress in treating chronic granulomatous disease

Volume: 192, Issue: 2, Pages: 251 - 264
Published: Jul 8, 2020
Abstract
Chronic granulomatous disease is a primary immunodeficiency due to a defect in one of six subunits that make up the nicotinamide adenine dinucleotide phosphate oxidase complex. The most commonly defective protein, gp91phox, is inherited in an X-linked fashion; other defects have autosomal recessive inheritance. Bacterial and fungal infections are common presentations, although inflammatory complications are increasingly recognized as a...
Paper Details
Title
Progress in treating chronic granulomatous disease
Published Date
Jul 8, 2020
Volume
192
Issue
2
Pages
251 - 264
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