Coordination of injectable self-healing hydrogel with Mn-Zn ferrite@mesoporous silica nanospheres for tumor MR imaging and efficient synergistic magnetothermal-chemo-chemodynamic therapy

Compared to conventional chemotherapy with subcutaneous and intravenous injection, injection of self-healing hydrogel drug-delivery system to tumor site brings less toxicity for normal tissues, but also better specificity for tumor cells on account of spontaneous repair and better retention. More importantly, it is essential to introduce multifunctional nanomaterials into self-healing hydrogel loading chemotherapeutic drugs to significantly...