Pathogenic role of human C-reactive protein in diabetic retinopathy

Purpose: Elevated blood levels of C-reactive protein (CRP) are associated with both type 1 and type 2 diabetes and diabetic complications, such as diabetic retinopathy (DR). However, its pathogenic role in DR remains unknown. The present study aims to investigate the potential role of CRP in DR pathogenesis and explore its underlying mechanism. Materials and methods: Human CRP transgenic (hCRP-Tg) rats were employed for streptozotocin...