New Flavoalkaloids with Potent α-Glucosidase and Acetylcholinesterase Inhibitory Activities from Yunnan Black Tea 'Jin-Ya'.

Published on Jul 14, 2020in Journal of Agricultural and Food Chemistry4.192
· DOI :10.1021/ACS.JAFC.0C02401
Na Li61
Estimated H-index: 61
(CAS: Chinese Academy of Sciences),
Na Li16
Estimated H-index: 16
(CAS: Chinese Academy of Sciences)
+ 3 AuthorsYing-Jun Zhang28
Estimated H-index: 28
(CAS: Chinese Academy of Sciences)
As the subgroup of flavoalkaloids, N-ethyl-2-pyrrolidinone substituted flavan-3-ols are reported to possess various biological activities that may play important roles in the beneficial healthcare ...
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#1Shi-Yu Liu (AAU: Anhui Agricultural University)
#2Yuan-Yuan Zhang (AAU: Anhui Agricultural University)
Last. Guan-Hu Bao (AAU: Anhui Agricultural University)
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Abstract null null Formation of catechins-human serum albumin (HSA) complex contributes to stably transporting catechins and regulating their bioavailability. Recently, a new class of catechins namely flavoalkaloids have been reported from tea. The unique structural modification with an N-ethyl-2-pyrrolidinone ring at catechins from these flavoalkaloids has raised our interest in their HSA binding affinity. Thus, we investigated the interaction between HSA and flavoalkaloids by molecular docking...
#1Xian-Li Zhou (GLMU: Guilin Medical University)H-Index: 3
#2Shan-Bin Li (GLMU: Guilin Medical University)
Last. Cheng-Qin Liang (GLMU: Guilin Medical University)H-Index: 3
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Abstract Thirteen undescribed dammarane triterpenoid saponins (cypaliurusides A–M), including eleven seco-dammarane type triterpenoids, were isolated from Cyclocarya paliurus. Each of these compounds has the unique feature of having a monosaccharide attached to C-11, rather than C-12, compared to the same type of saponins found in this plant. The structures of them were determined by comprehensive analysis of 1D, 2D NMR and HRESIMS data. Cypaliuruside J showed significant α-glucosidase inhibitor...
#1Qiang-Qiang Shi (CAS: Chinese Academy of Sciences)H-Index: 4
#2Shuang-Yang Lu (CAS: Chinese Academy of Sciences)H-Index: 6
Last. Ming-Hua Qiu (CAS: Chinese Academy of Sciences)H-Index: 26
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The seed oil of Prinsepia utilis is extensively used as an edible oil by the nationalities of Naxi, Tibetan, and Mosuo in China, which is particularly good for beauty care and has a health protection function. A large amount of industrial waste is thrown away during the production process of seed oil. Therefore, to recover bioactive compounds from the oil residue of P. utilis is environmentally friendly and economically important. For this purpose, the chemical constituents of the P. utilis oil ...