Cancer Stem Cell-Inducing Media Activates Senescence Reprogramming in Fibroblasts
Abstract
Cellular senescence is a tumor-suppressive mechanism blocking cell proliferation in response to stress. However, recent evidence suggests that senescent tumor cells can re-enter the cell cycle to become cancer stem cells, leading to relapse after cancer chemotherapy treatment. Understanding how the senescence reprogramming process is a precursor to cancer stem cell formation is of great medical importance. To study the interplay between...
Paper Details
Title
Cancer Stem Cell-Inducing Media Activates Senescence Reprogramming in Fibroblasts
Published Date
Jun 30, 2020
Journal
Volume
12
Issue
7
Pages
1745 - 1745
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