High‐sensitivity CEST mapping using a spatiotemporal correlation‐enhanced method

To obtain high-sensitivity CEST maps by exploiting the spatiotemporal correlation between CEST images.A postprocessing method accomplished by multilinear singular value decomposition (MLSVD) was used to enhance the CEST SNR by exploiting the correlation between the Z-spectrum for each voxel and the low-rank property of the overall CEST data. The performance of this method was evaluated using CrCEST in ischemic mouse brain at 11.7 tesla. Then,...