Performance comparison of modified ComBat for harmonization of radiomic features for multicenter studies
Abstract
Multicenter studies are needed to demonstrate the clinical potential value of radiomics as a prognostic tool. However, variability in scanner models, acquisition protocols and reconstruction settings are unavoidable and radiomic features are notoriously sensitive to these factors, which hinders pooling them in a statistical analysis. A statistical harmonization method called ComBat was developed to deal with the “batch effect” in gene expression...
Paper Details
Title
Performance comparison of modified ComBat for harmonization of radiomic features for multicenter studies
Published Date
Jun 24, 2020
Journal
Volume
10
Issue
1
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