Regulator of Calcineurin (RCAN): Beyond Down Syndrome Critical Region.
Abstract
The regulator of calcineurin (RCAN) was first reported as a novel gene called DSCR1, encoded in a region termed the Down syndrome critical region (DSCR) of human chromosome 21. Genome sequence comparisons across species using bioinformatics revealed three members of the RCAN gene family, RCAN1, RCAN2, and RCAN3, present in most jawed vertebrates, with one member observed in most invertebrates and fungi. RCAN is most highly expressed in brain and...
Paper Details
Title
Regulator of Calcineurin (RCAN): Beyond Down Syndrome Critical Region.
Published Date
Aug 31, 2020
Journal
Volume
43
Issue
8
Pages
671 - 685
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