Rosmarinic Acid Exhibits Anticancer Effects via MARK4 Inhibition
Abstract
Microtubule affinity regulating kinase (MARK4) is a potential drug target for different types of cancer as it controls the early step of cell division. In this study, we have screened a series of natural compounds and finally identified rosmarinic acid (RA) as a potential inhibitor of MARK4. Molecular docking and 500 ns all-atom simulation studies suggested that RA binds to the active site pocket of MARK4, forming enough number of non-covalent...
Paper Details
Title
Rosmarinic Acid Exhibits Anticancer Effects via MARK4 Inhibition
Published Date
Jun 25, 2020
Journal
Volume
10
Issue
1
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