Pharmacologic inhibition of mTORC1 mimics dietary protein restriction in a mouse model of lactation
Volume: 11, Issue: 1
Published: Jun 29, 2020
Abstract
Understanding the mechanisms of N utilization for lactation can lead to improved requirement estimates and increased efficiency, which modern dairy diets currently fail to maximize. The mechanistic target of rapamycin complex 1 (mTORC1) is a central hub of translation regulation, processing extra- and intra-cellular signals of nutrient availability and physiological state, such as amino acids and energy. We hypothesized that dietary amino acids...
Paper Details
Title
Pharmacologic inhibition of mTORC1 mimics dietary protein restriction in a mouse model of lactation
Published Date
Jun 29, 2020
Volume
11
Issue
1
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