Microfluidic liposomes-anchored microgels as extended delivery platform for treatment of osteoarthritis

Immobilizing liposomes in the hydrogel matrix network has become an effective strategy to protect liposomes against rapid clearance in the body, thus facilitating their localized drug delivery in a controlled and sustained manner for a long period. However, the low efficiency of drug delivery and short joint retention time seriously weaken its therapeutic efficacy. Herein, an efficient delivery platform was designed to anchor liposomes by...