Hypertension in a preterm after indomethacin use for patent ductus arteriosus

Non-steroidal anti-inflammatory drugs have been associated with hypertension in adults. We report an infant who developed hypertension after indomethacin use for patent ductus arteriosus. The patient was delivered at 31 weeksʼ gestation. Patent ductus arteriosus was detected on day 2. Indomethacin was given intravenously from day 2 to day 6. The ductus arteriosus was closed on day 7. On day 8, urine output decreased and serum creatinine...