Cascade of reactive oxygen species generation by polyprodrug for combinational photodynamic therapy

Volume: 255, Pages: 120210 - 120210
Published: Oct 1, 2020
Abstract
The redox status of cancer cells is well regulated by the balance between the reactive oxygen species (ROS) generation and elimination. Thus, the overall elevation of ROS level above the cellular tolerability threshold would lead to apoptotic or necrotic cell death. Herein, cinnamaldehyde (CA), a kind of oxidative stress amplified agent, was combined with photosensitizer pheophorbide A (PA) to promote the generation of ROS though synergistically...
Paper Details
Title
Cascade of reactive oxygen species generation by polyprodrug for combinational photodynamic therapy
Published Date
Oct 1, 2020
Volume
255
Pages
120210 - 120210
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