L-type amino acid transporter 1, LAT1, in growth hormone-producing pituitary tumor cells

Volume: 515, Pages: 110868 - 110868
Published: Sep 1, 2020
Abstract
Pituitary tumors (PTs) can cause significant mortality and morbidity due to limited therapeutic options. L-type amino acid transporters (LATs), in particular, the LAT1 isoform, is expressed in a variety of tumor cells. Pharmacological inhibition or genetic ablation of LAT1 can suppress leucine transport into cancer cells, resulting in suppression of cancer cell growth. However, roles of LAT1 in PTs have not been elucidated. Therefore, we...
Paper Details
Title
L-type amino acid transporter 1, LAT1, in growth hormone-producing pituitary tumor cells
Published Date
Sep 1, 2020
Volume
515
Pages
110868 - 110868
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