Second harmonic generation characterization of collagen in whole bone
Abstract
Bone is a unique biological composite material made up of a highly structured collagen mesh matrix and mineral deposits. Although mineral provides stiffness, collagen’s secondary organization provides a critical role in bone elasticity. Here, we performed polarimetric analysis of bone collagen fibers using second harmonic generation (SHG) imaging to evaluate lamella sheets and collagen fiber integrity in intact cranial bone. Our polarimetric...
Paper Details
Title
Second harmonic generation characterization of collagen in whole bone
Published Date
Jul 17, 2020
Journal
Volume
11
Issue
8
Pages
4379 - 4379
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