Recent Advances in the Role of Natural Killer Cells in Acute Kidney Injury

Growing evidences are revealing a central role for Natural Killer (NK) cells, cytotoxic cells belonging to the emerging family of Innate Lymphoid Cells (ILCs), in acute and chronic forms of renal disease. NK cell effector functions include both the recognition and elimination of virus infected and tumor cells and the capability of sensing pathogens through Toll-like receptor (TLR) engagement. Notably, they also display immune regulatory...