MicroRNA‑505‑3p inhibits development of glioma by targeting HMGB1 and regulating AKT expression

Previous studies have reported that microRNA (miR)‑505 exhibits important effect in human cancers. However, the regulatory mechanism of miR‑505‑3p/high‑mobility group box 1 (HMGB1) axis is still unclear in glioma. Therefore, the regulatory mechanism of miR‑505‑3p/HMGB1 axis in glioma was illuminated. Expression of miR‑505‑3p and HMGB1 was observed by RT‑qPCR. Protein expression was measured by western blot analysis. Dual luciferase assay was...