1059-P: Additive Manufactured Macroencapsulation Devices for Islet Cell Replacement Therapy
Abstract
Islet encapsulation devices can induce a Foreign Body Response (FBR) and the formation of a dense avascular fibrotic capsule. This FBR is heightened when the device has a smooth surface as fibrous tissue is unable to adhere, instigating a substantial immunological reaction, islet death and ultimately implant failure. In this study, we examine whether additive manufactured multiscale porous devices promote optimal tissue integration and...
Paper Details
Title
1059-P: Additive Manufactured Macroencapsulation Devices for Islet Cell Replacement Therapy
Published Date
Jun 1, 2020
Journal
Volume
69
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