PKD2/polycystin-2 induces autophagy by forming a complex with BECN1
Abstract
Macroautophagy/autophagy is an intracellular process involved in the breakdown of macromolecules and organelles. Recent studies have shown that PKD2/PC2/TRPP2 (polycystin 2, transient receptor potential cation channel), a nonselective cation channel permeable to Ca2+ that belongs to the family of transient receptor potential channels, is required for autophagy in multiple cell types by a mechanism that remains unclear. Here, we report that PKD2...
Paper Details
Title
PKD2/polycystin-2 induces autophagy by forming a complex with BECN1
Published Date
Jun 30, 2020
Journal
Volume
17
Issue
7
Pages
1714 - 1728
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