Original paper

Mechanistic modeling of chromatin folding to understand function

Volume: 17, Issue: 8, Pages: 767 - 775
Published: Jun 8, 2020
Abstract
Experimental approaches have been applied to address questions in understanding three-dimensional chromatin organization and function. As datasets increase in size and complexity, it becomes a challenge to reach a mechanistic interpretation of experimental results. Polymer simulations and mechanistic modeling have been applied to explain experimental observations and their links to different aspects of genome function. Here we provide a guide...
Paper Details
Title
Mechanistic modeling of chromatin folding to understand function
Published Date
Jun 8, 2020
Volume
17
Issue
8
Pages
767 - 775
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