Synthesis of sialic acid 9-C and 3-OH derivatives: the challenge of developing new antibacterial drugs by inhibition of sialic acid uptake
Published: Jan 1, 2018
Abstract
According to the World Health Organization (WHO), antibiotic resistance is a serious threat to our society. Infections with multi-resistant bacteria are causing increased mortality and social costs. Few new drugs are in the pipeline and no prospective of significantly improving the situation seems to be present. Sialic acids are a wide family of acidic sugars found in the terminal position of glycan chains. Due to their terminal position and...
Paper Details
Title
Synthesis of sialic acid 9-C and 3-OH derivatives: the challenge of developing new antibacterial drugs by inhibition of sialic acid uptake
Published Date
Jan 1, 2018
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