Autologously Humanized Mice for Immune‐Oncologic Studies

Volume: 89, Issue: 1
Published: May 29, 2020
Abstract
With the rapid approval of immune checkpoint inhibitors for lung, melanoma, breast, genitourinary, and hematological malignancies, the hematopoietic cells in the tumor microenvironment (TME) are now considered an important, if not essential, consideration for cancer scientists. In many instances, syngeneic murine models have not been highly predictive for responsiveness in clinical trials. Our limited understanding of the human TME have,...
Paper Details
Title
Autologously Humanized Mice for Immune‐Oncologic Studies
Published Date
May 29, 2020
Volume
89
Issue
1
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