Advances in studies on chemical compositions of Alismatis Rhizoma and their biological activities

Published on Apr 1, 2020in China journal of Chinese materia medica
· DOI :10.19540/J.CNKI.CJCMM.20190616.201
Shan-Shan Liu1
Estimated H-index: 1
Shan-Shan Liu13
Estimated H-index: 13
(Peking Union Medical College)
+ 5 AuthorsLu Gao2
Estimated H-index: 2
Alismatis Rhizoma is a traditional Chinese medicine, which was widely used in clinical prescriptions and proprietary Chinese medicine. Over 220 compounds have been isolated from it, including triterpenoids, sesquiterpenoids, diterpenoids, polysaccharides, nitrogen compounds, phenylpropanoids, flavones and sterides. The pharmacological studies show that Alismatis Rhizoma exhibits diuretic, anti-urolithiatic, anti-hyperlipidemia, antidiabetics, antitumor, antioxidative, anti-inflammatory, anti-complementary activities, etc. In this review, the chemical compositions and its pharmacological activities of Alismatis Rhizoma in recent 50 years were summarized. The authors hope to provide references for further study, development and utilization of Alismatis Rhizoma.
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#1Chengfu Li (Yanbian University)
#2Wei Yan (Yanbian University)
Last. Changji Zheng (Yanbian University)
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Five compounds including three triterpenoids and two sesquiterpenes were isolated from Alimatis rhizoma. Their chemical structures were determined to be alisol B 23-acetate (1), alisol C 23-acetate (2), alisol B (3), alismol (4) and alismoxide (5) by various spectroscopic analysis, including 1H-NMR, 13C-NMR, HMBC and MS spectra. Compounds 1–5 were evaluated for their antibacterial potential against 6 strains of bacteria including three drug-resistant bacteria (one methicillin-resistant Staphyloc...
#1Yumeng Zhang (SPU: Shenyang Pharmaceutical University)H-Index: 4
#2Min Zhao (SPU: Shenyang Pharmaceutical University)H-Index: 8
Last. Miao Wang (SPU: Shenyang Pharmaceutical University)H-Index: 9
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Abstract Yinchen Wuling Powder (YCWLP) is a classic Chinese medicine prescription with a long history and has been commonly used for treating jaundice hepatitis, liver fibrosis, hyperlipidemia and early diabetes in clinical applications. However, the chemical composition of YCWLP is still unclear. In order to obtain the chemical profile of YCWLP, a systematic ultra-performance liquid chromatography coupled with fourier transform ion cyclotron resonance mass spectrometry (UPLC-FT-ICR-MS) method w...
#1Suying Liu (CDUTCM: Chengdu University of Traditional Chinese Medicine)
#2Hua Yan (CDUTCM: Chengdu University of Traditional Chinese Medicine)
Last. Yutong Cui (CDUTCM: Chengdu University of Traditional Chinese Medicine)
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Cervical cancer is one of the top lethal malignancies among women worldwide. The current treatment methods have so many drawbacks that new treatment methods need to be developed. Zhidai Decoction (ZDD) is an effective traditional Chinese herbal formulation for gynecological diseases. Its main effect is controlling abnormal leucorrhea which is a typical early clinical manifestation of cervical cancer. However, how ZDD directly affects cervical cancer has not been addressed. In this study, we esta...